Changes in schizophrenia diagnoses associated with cannabis use disorder
Comments
a_cardboard_box
mlyle
Maybe not even worse.
This is looking at what fraction of schizophrenia cases had significant cannabis use.
If more people use cannabis, there will be more of these cases, even if there's no causal link.
appstorelottery
Cannabis misuse appears linked to a larger share of schizophrenia cases as I understand it.
bb123
I'm not really surprised by this finding. My anecdotal experience has been that pretty much everyone knows a friend or a friend of a friend who smoked too much pot and had their life go off the rails. It is pretty clear to me that it is not a harmless herb despite that being the commonly held belief on places like Reddit.
Retric
Implying causality there is often misplaced. I’ve noticed some people smoke more after things start to fall apart from issues they have no control over, just as others binge eat when stressed.
It’s not a helpful coping mechanism, but there’s a reason double blind studies are considered so important. Untangling complex mechanisms especially when they have feedback in both directions is inherently difficult.
Aurornis
> My anecdotal experience has been that pretty much everyone knows a friend or a friend of a friend who smoked too much pot and had their life go off the rails
Sadly, I’m seeing a new trend of people taking too many psychedelics and going off the rails.
The way they’re being pushed as cure-alls for depression is getting scary.
One of my friends developed severe problems after following the microdosing trend. It developed slowly over a long period of time, but he thought he was okay because he was following one of those protocols from one of the biggest microdosing experts.
Loughla
Pot is one of those things that makes things worse if they're already going badly.
Like alcohol or opiates will make your good life bad if you fuck too hard with them.
Pot, in my experience, won't really ruin your life unless you're already on that path.
My thing is that it's mostly harmless, but the problem with it is that young people can become complacent with it. It won't necessarily ruin your life, but you'll be content to sit and veg your life away. So not bad, but not good.
bongodongobob
I don't think I do. I do know a lot who have fucked their lives with alcohol and opiates though.
HackerThemAll
Drinking too much coffee or even water can kill you. Too much sugar can kill you (albeit not too quickly). Obsessive eating or shopping can derail your life pretty quickly. Obsessive use of social media can induce depression. Some people kill themselves because of what they read or see in social media.
So it's not the legalization at fault, it's people who are overdosing any stuff that's available to them. Casual smoking a weed once a week won't harm you that much.
LoganDark
While I also have anecdotal experience that suggests early-life cannabis abuse can lead to short-term memory loss, I have not seen any evidence that it leads to much else. I would imagine that people with a genetic predisposition to schizophrenia would only not have it by chance, and that altering their brain with pretty much anything can risk upsetting that balance. Doesn't matter if it's weed, LSD, opioids... SSRIs, stimulants...
nick__m
According to what i remember reading in 2010 (maybe the science has changed in the last fifteen years but I doubt it)
People with the Val158Met COMT polymorphism are more susceptible to develop schizophrenia sooner if they are exposed to cannabis. And that genetic mutation make them more successible to have cannabis use disorder. Knowing that I don't understand the question that this study is attempting to answer.
HiroshiSan
A lot of people like to pretend that smoking weed is harmless.
I support legalization but from my personal experience, I’ve suffered psychosis twice after smoking weed, and that’s enough for me.
barnabyjones
I agree it can cause those effects but it always seemed to me that the weed is just causing sleep deprivation which eventually leads to psychosis. IME it's not much different from alcohol in that way, they both disturb REM sleep so you end up deprived with daily use. It's just more apparent with weed because you don't get the hangover effects, so it's easy to overuse.
monero-xmr
It is incredible that the slightest increase in any cancer associated with alcohol is immediately trumpeted, but no matter how much research shows marijuana has dangers, the stoners always brush it off.
Just accept the risks and live your life. Nothing is without risk. Drink your beer and smoke your joint, why bother living if you aren’t going to enjoy yourself
aurareturn
Schizophrenia symptoms:
Hallucinations (e.g., hearing voices), delusions (e.g., believing one has special powers), disorganized speech and behavior, reduced emotional expression, lack of motivation, withdrawal from social interactions, problems with attention, memory, and decision-making
Yep. Had nearly all of the above when I was bored out of my mind and smoked every single day during covid. I was working remotely and was high half of the time I worked. That went on for about 1 year. Thank goodness I was a mature adult when I first started and could eventually remember that life was better without weed. Sober for 1.5 years now.I highly recommend r/leaves to read other people's stories trying or wanting to quit weed.
Edit: For those wondering, after being sober for 1.5 years, I'm pretty much back to my old self. My memory took a while to come back but it's drastically better than it was when I first quit. I feel much more motivated in life. My relationships with family and friends are better and so is my physical health. I was smoking about 0.5g - 2g/day for 1.5 years.
highasfcuk
Nearly all are all symptoms of depression, delusions with manic depression. Nearly all are symptoms of being stoned too.
It's unlikely you were experiencing schizophrenia unless you were actually hearing voices, thinking that you were a "Targeted Invididual", things like that.
morpheos137
I have used weed a number of times. I also consider myself a schizoid personality disorder person. Supposedly that is on the very mild end of Schizophrenia. I have never found it to lead to psychosis or anxiety in myself.
All it does for me is make me feel relaxed and euphoric. If I use a lot I feel more relaxed and euphoric.
I am normally a person who is very detached from what people call a sense of self.
I believe this immunizes me from the anxiety many feel when losing self control under substances.
I do find annoying how many "pot heads" seem to think that weed is a panacea rather than a pacifier with some risks for some people.
Although the effects are different I would very much consider it akin to alcohol or an opiate.
If you have problems it will likely make them harder to deal with.
If you are just looking to relax or escape and are not prone to anxiety then it is effective but in my experience not much different from alcohol or opiates except less physical harms or potential for physical addiction.
I agree with the posters that for many if not most people, including myself, weed can give the illusion of some special insights or special connections to others but it is important to recognize just that, that this is an illusion, that our subjective feelings at any given time do not necessarily correspond to objective reality.
It is shocking to me how many people in all kinds of areas of life think that because they feel something is true it must be true or important or relevant.
Weed evidently makes many weed users feel it is a wonder drug, thus propagating and sustaining the mind virus.
I think it should be legal.
I also think if you want to be successful in life habitual use is ill-advised.
I can certainly see how for anxious, over thinking, controlling types it could lead to psychosis, like any number of other things, even including ideas. However I believe this effect is more due to a pre-existing neurotic psychology of the specific user rather than an intrinsic property of the drug.
But regardless it's not harmless.
Additionally the long term effects are not well known.
LoganDark
I've tried cannabis a few times but I couldn't get it to do nearly anything at all. I've tried a few different kinds and also tried THC tincture, but could never get anything to happen other than some slight dissociation. Is that "stoned"? Is my brain just not receptive to it or something?
portaouflop
Every human brain is different, some smoke a lot of pot and develop serious mental issues— others smoke a ton for years and you don’t notice any change.
The problem imo with this kinds of studies is that people can’t take the nuance and rather see it as “weed = bad” or some other binary outcome.
Imo all drugs have a potential to be dangerous — all adults should have free agency what they do with their bodies.
Sure cannabis, alcohol or mushrooms are dangerous, but I would argue a society that makes their use completely illegal without nuance is not a free society
rufus_foreman
That was my experience also. I would smoke with my stoner friends, and it didn't seem to do much. I would think maybe I wasn't inhaling enough or something but then I would look in the mirror and my eyes were blood red.
I think it's just an expectations thing. I was doing max doses of acid for a long time before I ever used marijuana, and that ain't "some slight dissociation". On acid, you would watch the houses across the street stand up, join hands, and dance around in circles. Pot just didn't move the needle.
Perenti
I knew a few people when I was young (20s) that "pot does nothing" to them. Then one day they took a toke from a joint going round and were totally munged.
I've seen it a few times, and I have no idea why it's like that for some people.
Havoc
Sounds like a dosage situation. A lot of the tincture stuff just isn’t all that strong.
Effect wise - I mostly notice it in sensation of time. Two hours feels like four. And it’s not smooth flow of time - almost skips occasionally.
djkoolaide
People have this strange concept that weed is supposed to make you see rainbows and stuff lol. I'd say your experience is about normal.
iammrpayments
It just made me feel 0 anxiety, but I thought the experience was not good enough to justify breaking the law
csomar
Your brain is not receptive. This could be a worse, however. If you have schizophrenia within the family, you might be at risk. The doctor strongly recommended I do not take any cannabis because there is a risk it triggers a psychosis episode. I wouldn’t see cannabis having no effect as good news as that’s not representative of the average experience.
bongodongobob
This sounds snarky but you just didn't do enough.
ZYbCRq22HbJ2y7
[flagged]
Perenti
As a population based study, how did they control for other substances? Acid in particular is notorious for flashbacks years later that can be psychotic. I also note that the period in question is also associated with massive increase in methamphetamine abuse. Greater access to THC being associated with an increase in crazy people using it makes complete sense, but is a causal link between legislation and schizophrenia really demonstrated amongst chronic potheads (the study is about psychosis in people with CAD), that being the subject of the paper?
elevaet
Are acid flashbacks real? I thought that was an urban myth.. I've never had one and I don't think I've ever encountered someone who has. It seems like one of those drug war era scare tactics or viral rumours.
djaouen
I was diagnosed schizophrenic without any use of cannabis. What prize do I get????
sandworm101
The big question remains: is this downside worse than the innumerable and absolute known downsides associated with alcohol? If not, this is a purely acedemic issue.
xyst
Explains the downfall of Elmo [1]. Bro hasn’t been the same since that fateful day on JRE.
m3kw9
Don’t do drugs
ZYbCRq22HbJ2y7
Maybe an increase in misdiagnosis?
> The annual incidence of schizophrenia was stable over time, while the incidence of psychosis NOS increased from 30.0 to 55.1 per 100 000 individuals (83.7%) in the postlegalization period relative to the prelegalization period.
So increased cannabis use after legalization did not result in increased rates of schizophrenia, though it might have made some cases worse.